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Cell biology

Secretome

The secretome is the complete set of molecules, including proteins, lipids, and extracellular vesicles, that a cell or tissue releases into its surrounding environment.

Secretome characterization uses targeted assays such as ELISA panels for specific growth factors and cytokines. For Bio Xsomes, the supplier reports a growth-factor and cytokine panel as analytical findings only, not as a description of clinical effect.

Secretome composition varies by source cell or tissue type, culture conditions, and processing method, which is why published characterization data is specific to a given source and process rather than generalizable across all perinatal tissue or cell line-derived products.

A secretome or growth-factor panel describes what analytical testing found in a sample, reported as present or at a measured concentration. It is not a statement about physiological effect. Ask the supplier for the underlying characterization method and data behind any such panel, separate from any statement about use.

A secretome panel describes measured composition, not function, which is the distinction buyers should maintain when reviewing supplier characterization sheets.

Sources

  1. Minimal information for studies of extracellular vesicles 2023 (MISEV2023) ↗PMC
  2. Umbilical cord-derived Wharton's jelly for regenerative medicine: a systematic review ↗PMC