How pain management practices evaluate a new tissue and biologics supplier
Pain management and physical medicine practices typically start a new supplier relationship by reviewing sourcing and processing documentation rather than product claims. That review usually covers how tissue is recovered and screened, how a lot is released, and what third-party sterility testing was performed before the lot shipped.
Because exosome products and Wharton's jelly allografts sit in different parts of the federal regulatory framework, many practices route this review through their medical director or outside counsel before adding a product to their ordering list.
Des Moines
NPPES registry listings, primary taxonomy, retrieved 2026-10-27
39- Pain Medicine
- 11
- Physical Medicine & Rehabilitation
- 28
Account setup and ongoing support
Ordering with Precision Biologics requires an NPI-verified account, which a practice administrator can request directly. Once verified, the account has access to lot-specific documentation and can schedule a peer-to-peer call with physician-level staff to walk through paperwork and sourcing questions.
These calls are limited to documentation and sourcing; Precision Biologics does not provide guidance on injection technique, dosing, or patient selection.
Cold-chain receiving and documentation for Midwest clinics
Cryopreserved products are shipped overnight on dry ice in validated containers and require storage at -80 degrees Celsius on arrival; lyophilized formats are shelf-stable and ship per the insert included with the lot. Practices in Des Moines and across the Midwest should have a receiving plan in place, including freezer space, before the first order arrives.
Each lot carries a certificate of analysis, a donor eligibility summary, and a lot release record, available to verified accounts. Iowa practices should confirm their own regulatory posture and medical-director oversight requirements with the Iowa medical board and independent counsel.
FDA has stated there are no FDA-approved exosome products. Exosome products are generally regulated as biologic drugs under section 351 of the Public Health Service Act, not as 361 HCT/Ps. Purchase and clinical use decisions belong to the physician with their own regulatory counsel.
These products are not FDA approved or licensed for any disease or condition. Information is for licensed healthcare professionals and is not medical or legal advice.
Frequently asked questions
Who can open an ordering account with Precision Biologics?+
Accounts are limited to licensed physicians and clinics and require NPI verification. A pain management or physical medicine practice in Des Moines can request documentation access once its NPI has been confirmed.
What documentation is available for a specific product lot?+
Verified accounts can request a certificate of analysis, donor eligibility summary, and lot release record for each lot. Exosome products also include supplier-reported characterization data on request.
How should a Des Moines practice prepare to receive an order?+
Cryopreserved products arrive overnight on dry ice and need prompt transfer to -80 degree Celsius storage. Lyophilized products are shelf-stable and shipped according to the insert included with that lot.