What a pain management practice should ask for before ordering
Pain management and physical medicine groups considering a new biologics line typically request the lot-specific certificate of analysis, donor eligibility summary, and lot release record before committing to a first order.
For exosome products, Precision Biologics also shares the available characterization data (assay results, particle counts, and marker identification reported by the supplier), presented strictly as analytical findings rather than as claims about what the product does once administered.
Los Angeles
NPPES registry listings, primary taxonomy, retrieved 2026-10-27
364- Pain Medicine
- 164
- Physical Medicine & Rehabilitation
- 200
NPI-verified ordering
Every account is opened for a licensed professional and checked against an NPI number before the first shipment goes out; Precision Biologics does not sell to patients or unverified buyers.
Interventional pain groups with several physicians on staff can verify each ordering physician separately, which keeps purchasing records tied to the individual who authorized the order.
Receiving dry-ice and shelf-stable shipments
Cryopreserved Wharton's jelly products ship overnight on dry ice and need immediate transfer to -80 degree Celsius storage; practices running multiple procedure days per week typically assign one staff member to confirm temperature and lot number against the packing slip at intake.
Lyophilized exosome products skip that step and remain shelf-stable, which some single-physician pain practices prefer to avoid freezer costs altogether. Use of either format is tracked by lot at the patient-record level once received.
Confirming scope and regulatory status with your own counsel
Precision Biologics does not advise on dosing, injection technique, or which pain indications a product might be used for; those are clinical and regulatory decisions that belong to the treating physician.
California pain practices should confirm licensing, scope-of-practice, and any product-specific regulatory questions with the Medical Board of California and their own legal counsel, not with a supplier's marketing material.
FDA has stated there are no FDA-approved exosome products. Exosome products are generally regulated as biologic drugs under section 351 of the Public Health Service Act, not as 361 HCT/Ps. Purchase and clinical use decisions belong to the physician with their own regulatory counsel.
These products are not FDA approved or licensed for any disease or condition. Information is for licensed healthcare professionals and is not medical or legal advice.
Frequently asked questions
Can a Los Angeles pain practice get characterization data for Bio Xsomes before ordering?+
Yes, exosome characterization data (assay, NTA, SP-IRIS results, and marker identification) is available to verified accounts on request.
Does Precision Biologics recommend specific pain indications for its products?+
No. Precision Biologics does not provide clinical guidance, dosing, or indication recommendations; those decisions remain with the treating physician.
Is there a minimum order size for a solo pain management practice in Los Angeles?+
Account setup is based on NPI verification rather than practice size; contact Precision Biologics directly for current ordering details.