Every lot a clinic receives carries a lot number and an associated storage window tied to the conditions it was validated under. Plan rotation around each lot's documented expiration date and storage conditions rather than receipt order alone.
This matters more for cryopreserved formats, where freezer space and shelf life are both constrained, than for formats described as shelf-stable at room temperature, though even shelf-stable lyophilized products carry their own storage guidance in the product insert. Tracking rotation by lot number, alongside chain-of-custody and patient-use records where a clinic maintains them, ties the rotation system to the same data used for traceability.
Choose a recordkeeping system with the compliance team that links inventory and patient-level lot records. The goal is operational: minimizing waste and keeping expired or near-expiry lots out of use, not a requirement imposed by any specific statute.
Rotating stock by each lot's documented expiration date, rather than by receipt order alone, reduces the chance of using a lot past its validated storage window.