Bakersfield
NPPES registry listings, primary taxonomy, retrieved 2026-10-27
27- Dermatology
- 13
- Plastic Surgery
- 14
Physician Supervision and Account Verification
Precision Biologics opens accounts for medspas only when a supervising physician's NPI number is part of the verification record, in addition to accounts for dermatology and plastic surgery practices ordering directly under a physician's own NPI.
Practices that operate across more than one location sometimes maintain a single verified account with the supervising physician's NPI attached to each location's orders, which keeps the record consistent across the group.
What to Request Before Stocking a New Product Line
Before adding either the Wharton's jelly or exosome product lines, most aesthetic practices ask for the certificate of analysis and donor eligibility summary tied to the lot, along with confirmation of how the product was characterized and tested.
For exosome products specifically, Precision Biologics makes supplier characterization data, including particle concentration, marker identification, and growth factor and cytokine panel reporting, available on request, so a practice's medical director can review it directly.
Shipping and Storage in California
Cryopreserved Wharton's jelly product ships overnight on dry ice and requires -80 C storage once received; several of the exosome and lyophilized Wharton's jelly formats are shelf-stable and do not need a freezer, which some smaller medspas prefer given limited back-office storage.
Whichever format is ordered, the lot number should be entered into the practice's inventory log on arrival so it can be matched to the patient record later.
Confirming Regulatory Fit with Counsel
FDA has stated that there are no FDA-approved exosome products and that these products are generally regulated as biologic drugs; purchase and use decisions for an exosome product remain with the physician and their own regulatory counsel. Whether a particular Wharton's jelly product and intended use meet the criteria in 21 CFR 1271.10 is likewise a determination for the practice and its counsel, checked against the California medical board's requirements for the supervising physician.
Precision Biologics does not advise on clinical use, dosing or procedures; account setup includes a peer-to-peer call limited to reviewing product documentation.
FDA has stated there are no FDA-approved exosome products. Exosome products are generally regulated as biologic drugs under section 351 of the Public Health Service Act, not as 361 HCT/Ps. Purchase and clinical use decisions belong to the physician with their own regulatory counsel.
These products are not FDA approved or licensed for any disease or condition. Information is for licensed healthcare professionals and is not medical or legal advice.
Frequently asked questions
Can a medspa open an account directly, or does it need a supervising physician?+
Medspa accounts are verified against a supervising physician's NPI number; Precision Biologics sells only to licensed clinics, physician-supervised medspas, and physicians.
Are exosome products like Bio Xsomes FDA approved?+
No. FDA has stated there are no FDA-approved exosome products; purchase and use decisions rest with the physician and their counsel.
What documentation can I review before adding a new product line?+
Certificate of analysis, donor eligibility summary, lot release record, and for exosome products, supplier characterization data, are available to verified accounts on request.