Greenville
NPPES registry listings, primary taxonomy, retrieved 2026-10-27
127- Orthopaedic Surgery
- 127
How orthopedic surgery centers in the Southeast evaluate a biologics distributor
Orthopedic practices and surgery centers across the Southeast commonly run new biologics vendors through the same supply-chain review used for implants and other procedural products: a documentation check, a traceability review, and confirmation that the medical director signs off before the product is added to inventory.
Precision Biologics supports that review by providing a certificate of analysis, donor eligibility summary, and lot release record to verified accounts, along with supplier characterization data for exosome products on request.
NPI-verified ordering access
Access to pricing and ordering opens only after NPI verification against the NPPES registry. A surgery center can designate one ordering contact, or route verification through its own compliance team if that is how other vendor relationships are already managed.
- NPI number for the ordering provider or entity
- Confirmation of licensed status
- A designated ordering and documentation contact
Shipping cryopreserved product into the Southeast
Cryopreserved Wharton's jelly and exosome products ship overnight on dry ice in validated containers maintained near -80 degrees C, using standard overnight carrier networks rather than a regional distribution hub. Surgery centers should plan receiving around business-day delivery windows and confirm a staff member is available to log the lot identifier on arrival.
Lyophilized formats, where available, do not require the same cryogenic handling and follow the storage and reconstitution instructions supplied with the lot.
Confirming regulatory posture with counsel
Whether a given intended use for a Wharton's jelly or exosome product fits a surgery center's existing regulatory framework, including how it is evaluated under 21 CFR 1271.10, is a determination for the center's medical director and legal counsel. Precision Biologics does not advise on clinical use, dosing, or procedures.
We recommend verifying licensure and supervision questions directly with the South Carolina medical board and independent counsel before adding any new product to a procedure.
FDA has stated there are no FDA-approved exosome products. Exosome products are generally regulated as biologic drugs under section 351 of the Public Health Service Act, not as 361 HCT/Ps. Purchase and clinical use decisions belong to the physician with their own regulatory counsel.
These products are not FDA approved or licensed for any disease or condition. Information is for licensed healthcare professionals and is not medical or legal advice.
Frequently asked questions
How many orthopedic providers does Precision Biologics serve in Greenville?+
We do not publish customer counts. NPPES registry data retrieved October 27, 2026 lists 127 individually registered providers under the Orthopaedic Surgery taxonomy with a primary location in Greenville, but that figure describes the registry, not our customer base.
Can a Greenville-based surgery center open an account directly?+
Yes. Any licensed orthopedic practice or surgery center can apply for an NPI-verified account regardless of location, including those based in Greenville.
What happens if a cryopreserved shipment arrives outside business hours?+
Shipments are scheduled for overnight delivery on business days. Your account contact can help coordinate delivery timing before the order ships to avoid an unattended cold-chain delivery.