Lyophilization is a freeze-drying process that produces a dry, shelf-stable format without cryogenic storage. PB's Bio DPM is one such lyophilized Wharton's jelly product. Handling, storage and any reconstitution steps follow the product insert supplied with each lot.
Because the format does not require frozen transport, a lyophilized allograft reduces the cold-chain burden on both the supplier and the clinic, which can simplify shipping logistics and inventory rotation. It does not, however, remove the need to follow the supplier's specified storage temperature and humidity limits, which still apply to shelf-stable products.
Before stocking a lyophilized product, buyers should request the product insert, the certificate of analysis for the specific lot, and the supplier's storage specifications, and should track shelf-life dating for lyophilized inventory with the same lot-level discipline used for cryopreserved products.
Shelf-stable does not mean unconditional: clinics should still follow the supplier's storage and handling specifications and track lyophilized inventory by lot and expiration.